Modified oligonucleotides
Author (Corporation)
Publication date
08.01.1998
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Type
12 - Patent
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Pages / Duration
Patent number
WO9800434
Publisher / Publishing institution
World Intellectual Property Organization
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Assignee
Novartis AG
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Abstract
It is one object of the present invention to provide an oligonucleotide of formula (1): 5'-(U)n-3' in which U is an identical or different radical of a natural or a synthetic nucleoside, wherein the oligonucleotide comprises at least one modified nucleotide dimer comprising two nucleoside analogs connected via an amide-bond that has a certain configuration; the synthesis of these compounds and their use in pharmaceutical preparations.
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Subject (DDC)
500 - Naturwissenschaften und Mathematik
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Created during FHNW affiliation
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Citation
DE MESMAEKER, Alain, Sebastian WENDEBORN und Jaques LEBRETON, 1998. Modified oligonucleotides. 8 Januar 1998. World Intellectual Property Organization. Verfügbar unter: https://doi.org/10.26041/fhnw-9970