Developing an automated preparation of microbiological samples for MALDI-TOF
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Authors
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Publication date
2025
Type of student thesis
Master
Course of study
Life Science MSLS
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11 - Student thesis
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Hochschule für Life Sciences FHNW
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Muttenz
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mabritec
CTC Analytics
CTC Analytics
Abstract
Bacteria play crucial roles in fields like food, environment, and human health. While some microorganisms are beneficial, such as those in the human gut aiding digestion, others are pathogenic, causing diseases like tuberculosis and Lyme disease [1,2]. Identifying bacteria at the species level is essential for an effective treatment, as susceptibility to antimicrobial agents can vary between species. However, clinical laboratories often rely on broader, less precise identifications, which can lead to a non effective treatment and/or the overuse of broad-spectrum antibiotics, contributing to antibiotic resistance [3]. This could be avoided with a proper sample preparation of the bacteria, which often takes more time. An automated process using a CTC PAL system would be cheap and quick, with the advantage to more precise identification of bacteria species.
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English
Created during FHNW affiliation
Yes
Strategic action fields FHNW
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Review
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Citation
Provoost, J. (2025). Developing an automated preparation of microbiological samples for MALDI-TOF [Hochschule für Life Sciences FHNW]. https://doi.org/10.26041/fhnw-15118