Electrospray mediated localized and targeted chemotherapy in a mouse model of lung cancer

dc.accessRightsAnonymous*
dc.contributor.authorHradetzky, David
dc.contributor.authorGazdhar, Amiq
dc.contributor.authorRuzgys, Paulius
dc.contributor.authorBöhringer, Stephan
dc.contributor.authorSila Dokumaci, Ayse
dc.contributor.authorHari, Yvonne
dc.contributor.authorSchürch, Christian
dc.contributor.authorBrühl, Frido
dc.contributor.authorSchürch, Stefan
dc.contributor.authorSönke, Szidat
dc.contributor.authorRiether, Carsten
dc.contributor.authorSatkauskas, Saulius
dc.contributor.authorGeiser, Thomas
dc.date.accessioned2022-03-14T08:57:16Z
dc.date.available2022-03-14T08:57:16Z
dc.date.issued2021-04-21
dc.description.abstractAn advanced stage, centrally localized invasive tumor is a major cause of sudden death in lung cancer patients. Currently, chemotherapy, radiotherapy, laser ablation, or surgical resection if possible are the available state-of-the-art treatments but none of these guarantee remedy or long-term relief and are often associated with fatal complications. Allowing localized chemotherapy, by direct and confined drug delivery only at the tumor site, could be a promising option for preoperative down staging or palliative therapy. Here we report the localized and targeted application of intra tumor delivery of chemotherapeutics using a novel device based on the principle of electrospray.en_US
dc.identifier.doi10.3389/fphar.2021.643492
dc.identifier.issn1663-9812
dc.identifier.urihttps://irf.fhnw.ch/handle/11654/33350
dc.identifier.urihttps://doi.org/10.26041/fhnw-4131
dc.language.isoen_USen_US
dc.publisherFrontiersen_US
dc.relation.ispartofFrontiers in Pharmacologyen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/en_US
dc.subjectOcalized and targeted therapyen_US
dc.subjectElectrosprayen_US
dc.subjectNovel cancer treatmenten_US
dc.subjectCoulomb repulsionen_US
dc.subjectLocalized tumor treatmenten_US
dc.titleElectrospray mediated localized and targeted chemotherapy in a mouse model of lung canceren_US
dc.type01A - Beitrag in wissenschaftlicher Zeitschrift
dspace.entity.typePublication
fhnw.InventedHereYesen_US
fhnw.IsStudentsWorknoen_US
fhnw.ReviewTypeAnonymous ex ante peer review of a complete publicationen_US
fhnw.affiliation.hochschuleHochschule für Life Sciences FHNWde_CH
fhnw.affiliation.institutInstitut für Medizintechnik und Medizininformatikde_CH
fhnw.openAccessCategoryGolden_US
fhnw.publicationStatePublisheden_US
fhnw.specialIssueSection: Translational Pharmacology
relation.isAuthorOfPublicationc9dfc5bf-b9cd-4a1b-b606-eee6c639fd56
relation.isAuthorOfPublication.latestForDiscoveryc9dfc5bf-b9cd-4a1b-b606-eee6c639fd56
Dateien

Originalbündel

Gerade angezeigt 1 - 1 von 1
Vorschaubild
Name:
fphar-12-643492.pdf
Größe:
2.1 MB
Format:
Adobe Portable Document Format
Beschreibung: