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dc.contributor.authorStübinger, Stefan
dc.contributor.authorBucher, Ramon
dc.contributor.authorKronen, Peter
dc.contributor.authorSchlottig, Falko
dc.contributor.authorvon Rechenberg, Brigitte
dc.date.accessioned2016-03-18T11:11:19Z
dc.date.available2016-03-18T11:11:19Z
dc.date.issued2016-02-22
dc.identifier.urihttp://hdl.handle.net/11654/17636
dc.description.abstractAim: The ligature-induced defect model still remains the model of first choice to experimentally investigate the cause, effect and treatment approaches of periimplantitis. It was the aim of the present in-vivo trail to revisit the ligature-induced peri-implantitis minipig model regarding its current scientific value and ethical justification in implant research. Materials and methods: Six minipigs were used for the analysis of peri-implant hard and soft tissue structures. Animals were randomly allocated to an experimental silk ligature-induced peri-implantitis group (n=4 animals) and a reference healthy group (n=2 animals). After six weeks mean pocket depths (PD) and bleeding on probing (BOP) measurements were performed just before animals were sacrificed. Results: Overall, ligature-induced peri-implantitis provoked a local inflammation around the experimental implants. Additionally, a loss of crestal bone surrounding the implants could be detected. Mean pocket depths (PD) were 2.2 ± 1.1 mm for healthy animals and 5.4 ± 1.9 mm for peri-implantitis sites. Healthy sites showed a BOP of 60%, whereas peri-implantitis sites disclosed a BOP of 90% within 10 s after probing. Conclusion: Clinical, radiological and histological findings of the present animal experiment supported the overall applicability of the ligature-induced periimplantitis minipig model. A rapid breakdown of peri-implant hard tissues could be detected mainly on the buccal side.
dc.description.urihttp://periodontics-prosthodontics.imedpub.com/ligatureinduced-periimplantitis-inminipigs-revisited.php?aid=8443
dc.language.isoen
dc.relation.ispartofPeriodontics and Prosthodontics: Open Access
dc.accessRightsAnonymous
dc.titleLigature-Induced Peri-Implantitis in Minipigs Revisited
dc.type01 - Zeitschriftenartikel, Journalartikel oder Magazin
dc.audienceScience
fhnw.publicationStatePublished
fhnw.ReviewTypeAnonymous ex ante peer review of a complete publication
fhnw.InventedHereYes
fhnw.PublishedSwitzerlandYes
fhnw.pagination-
fhnw.IsStudentsWorkno
fhnw.publicationOnlineJa


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