Auflistung nach Autor:in "Lebreton, Jaques"

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  • Vorschaubild
    Publikation
    Modified oligonucleotides
    (World Intellectual Property Organization, 08.01.1998) De Mesmaeker, Alain; Wendeborn, Sebastian; Lebreton, Jaques
    It is one object of the present invention to provide an oligonucleotide of formula (1): 5'-(U)n-3' in which U is an identical or different radical of a natural or a synthetic nucleoside, wherein the oligonucleotide comprises at least one modified nucleotide dimer comprising two nucleoside analogs connected via an amide-bond that has a certain configuration; the synthesis of these compounds and their use in pharmaceutical preparations.
    12 - Patent