Institut für Medizintechnik und Medizininformatik
Dauerhafte URI für die Sammlunghttps://irf.fhnw.ch/handle/11654/23
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12 Ergebnisse
Ergebnisse nach Hochschule und Institut
Publikation Miniaturization of stent prototypes by µSLM(Hochschule für Life Sciences FHNW, 2024) Wasmer, Larissa; de Wild, Michael; Seiler, Daniel; Politecnico di Torino11 - Studentische ArbeitPublikation Atlas-Based Segmentation Algorithm(Hochschule für Life Sciences FHNW, 2024) Kohler, Roger; Vogel, Dorian; Linköpings Universitet11 - Studentische ArbeitPublikation Quantitative assessment of repetitive lower limb movements used in the MDS-UPDRS-III scale in healthy subjects(Hochschule für Life Sciences FHNW, 2024) Hunziker, Sven; Hemm-Ode, Simone; Vogel, Dorian; Kalt, Denise; Kantonsspital Baden AG, Baden AG11 - Studentische ArbeitPublikation Robustness comparison of optimization techniques in Intensity Modulated Proton Therapy (IMPT)(Hochschule für Life Sciences FHNW, 2024) Hagmann, Virgile; Knopf, Antje; Paul Scherrer Institut, Villigen11 - Studentische ArbeitPublikation Stimmanalyse zur Evaluierung des Leidens bei Patienten mit Krebs(Hochschule für Life Sciences FHNW, 2024) Dere, Türkmen; Hemm-Ode, Simone; Kantonsspital Baselland, Liestal; Palliativzentrum Hildegard, Basel11 - Studentische ArbeitPublikation Analysis of Patient Reported Outcome Measures (PROMs)(Hochschule für Life Sciences FHNW, 2024) Schlumpf, Oliver; Kahraman, Abdullah; Luzerner Kantonsspital (LUKS); Swiss Sarcoma Network (SSN)11 - Studentische ArbeitPublikation Investigation of different quality assessment procedures for fast and reliable validation of CBCT-based synthetic CTs(Hochschule für Life Sciences FHNW, 2024) Maurenbrecher, Joakim; Knopf, Antje; Paul Scherrer Institut, Villigen11 - Studentische ArbeitPublikation A survey of practice patterns for real-time intrafractional motion-management in particle therapy(Elsevier, 26.04.2023) Zhang, Ye; Trnkova, Petra; Toshito, Toshiyuki; Heijmen, Ben; Richter, Christian; Aznar, Marianne; Albertini, Francesca; Bolsi, Alexandra; Daartz, Juliane; Bertholet, Jenny; Knopf, Antje01A - Beitrag in wissenschaftlicher ZeitschriftPublikation Increased construct stiffness with meniscal repair sutures and devices increases the risk of cheese-wiring during biomechanical load-to-failure testing(SAGE, 15.06.2021) Müller, Sebastian; Schwenk, Tanja; de Wild, Michael; Dimitrou, Dimitris; Rosso, ClaudioBackground: Cheese-wiring, the suture that cuts through the meniscus, is a well-known issue in meniscal repair. So far, contributing factors are neither fully understood nor sufficiently studied. Hypothesis/purpose: To investigate whether the construct stiffness of repair sutures and devices correlates with suture cut-through (cheese-wiring) during load-to-failure testing. Study design: Controlled laboratory study. Methods: In 131 porcine menisci, longitudinal bucket-handle tears were repaired using either inside-out sutures (n = 66; No. 0 Ultrabraid, 2-0 Orthocord, 2-0 FiberWire, and 2-0 Ethibond) or all-inside devices (n = 65; FastFix360, Omnispan, and Meniscal Cinch). After cyclic loading, load-to-failure testing was performed. The mode of failure and construct stiffness were recorded. A receiver operating characteristic curve analysis was performed to define the optimal stiffness threshold for predicting meniscal repair failure by cheese-wiring. The 2-tailed t test and analysis of variance were used to test significance. Results: Loss of suture fixation was the most common mode of failure in all specimens (58%), except for the Omnispan, which failed most commonly because of anchor pull-through. The Omnispan demonstrated the highest construct stiffness (30.8 ± 3.5 N/mm), whereas the Meniscal Cinch (18.0 ± 8.8 N/mm) and Ethibond (19.4 ± 7.8 N/mm) demonstrated the lowest construct stiffness. The Omnispan showed significantly higher stiffness compared with the Meniscal Cinch (P < .001) and Ethibond (P = .02), whereas the stiffness of the Meniscal Cinch was significantly lower compared with that of the FiberWire (P = .01), Ultrabraid (P = .04), and FastFix360 (P = .03). While meniscal repair with a high construct stiffness more often failed by cheese-wiring, meniscal repair with a lower stiffness failed by loss of suture fixation, knot slippage, or anchor pull-through. Meniscal repair with a stiffness >26.5 N/mm had a 3.6 times higher risk of failure due to cheese-wiring during load-to-failure testing (95% CI, 1.4-8.2; P < .0001). Conclusion: Meniscal repair using inside-out sutures and all-inside devices with a higher construct stiffness (>26.5 N/mm) was more likely to fail through suture cut-through (cheese-wiring) than that with a lower stiffness (≤26.5 N/mm). Clinical relevance: This is the first study investigating the impact of construct stiffness on meniscal repair failure by suture cut-through (cheese-wiring).01A - Beitrag in wissenschaftlicher ZeitschriftPublikation Clinical necessity of multi-image based (4DMIB) optimization for targets affected by respiratory motion and treated with scanned particle therapy – A comprehensive review(Elsevier, 02/2022) Czerska, Katarzyna; Fracchiolla, Francesco; Graeff, Christian; Molinelli, Silvia; Rinaldi, Ilaria; Rucincki, Antoni; Sterpin, Edmond; Stützer, Kristin; Trnkova, Petra; Zhang, Ye; Chang, Joe Y; Giap, Huan; Liu, Wei; Schild, Steven E; Simone, Charles B.; Lomax, Antony J; Meijers, Arturs; Knopf, Antje4D multi-image-based (4D MIB) optimization is a form of robust optimization where different uncertainty scenarios, due to anatomy variations, are considered via multiple image sets (e.g., 4DCT). In this review, we focused on providing an overview of different 4DMIB optimization implementations, introduced var- ious frameworks to evaluate the robustness of scanned particle therapy affected by breathing motion and summarized the existing evidence on the necessity of using 4DMIB optimization clinically. Expected potential benefits of 4DMIB optimization include more robust and/or interplay-effect-resistant doses for the target volume and organs-at-risk for indications affected by anatomical variations (e.g., breathing, peristalsis, etc.). Although considerable literature is available on the research and technical aspects of 4DMIB, clinical studies are rare and often contain methodological limitations, such as, limited patient number, motion amplitude, motion and delivery time structure considerations, number of repeat CTs, etc. Therefore, the data are not conclusive. In addition, multiple studies have found that robust 3D opti- mized plans result in dose distributions within the set clinical tolerances and, therefore, are suitable for a treatment of moving targets with scanned particle therapy. We, therefore, consider the clinical necessity of 4D MIB optimization, when treating moving targets with scanned particle therapy, as still to be demonstrated.01A - Beitrag in wissenschaftlicher Zeitschrift