Bayer-Oglesby, Lucy

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Bayer-Oglesby
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Lucy
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Bayer-Oglesby, Lucy

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Autor:in: Braun-Fahrländer, Charlotte × Autor:in: Camenzind, Markus × Autor:in: Künzli, Nino × Item-Typ: Publikation × Thema: 610 - Medizin und Gesundheit ×

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    Publikation
    Single pollutant versus surrogate measure approaches: Do single pollutant risk assessments underestimate the impact of air pollution on lung cancer risk?
    (Lippincott Williams & Wilkins, 2003) Röösli, Martin; Künzli, Nino; Schindler, Christian; Theis, Gaston; Bayer-Oglesby, Lucy; Mathys, Patrick; Camenzind, Markus; Braun-Fahrländer, Charlotte [in: Journal of Occupational and Environmental Medicine]
    Cancer risk as a result of air pollution may be quantified by different approaches. We compared the sum of unit risk based effects of single pollutants with an epidemiology-based method by using PM10 as a surrogate of the total air pollution. The excess rate for lung cancer cases attributable to an increase of 10 μg/m3 in average PM10 exposure was estimated from available cohort studies. Applying the epidemiology-based risk method to the air pollution situation in the Basel area (Switzerland) resulted in 13.3 (95% CI = 6.9–19.8) excess lung cancer cases per 100,000 person years. This estimate was considerably higher than the unit risk-based estimate yielding 1.1 (range, 0.45–2.8) cancer cases per 100,000 person years. We discuss these discrepancies in light of inherent differences between approaches in toxicology and epidemiology.
    01A - Beitrag in wissenschaftlicher Zeitschrift