2015-12-01, Bayer-Oglesby, Lucy

Das Krankenversicherungsgesetz erlaubt seit 2006 Schweizer Patientinnen und Patienten Behandlungen im Rahmen von Pilotprojekten im grenznahen Ausland in Anspruch zu nehmen. Im Raum Basel/Lörrach wurde von 2007 bis 2009 erstmals ein entsprechendes Projekt durchgeführt, das für die Jahre 2010 bis 2014 und 2015 bis 2018 verlängert wurde in Erwartung einer definitiven Gesetzesänderung. Der Evaluationsbericht der Phase II zeigt, dass sich die Zusammenarbeit im Projekt vor allem für Rehabilitationen von Schweizer Personen im Raum Lörrach bewährt hat. Nicht zu unterschätzen ist, dass ein Grossteil der grenzüberschreitenden Behandlungen unabhängig vom Pilotprojekt stattfindet, wobei die Patientenmobilität von Deutschland in die Schweiz jene in die umgekehrte Richtung um ein Vielfaches übertrifft.

2013-07-01T00:00:00Z, Haug, Severin, Schmid, Holger, Bayer-Oglesby, Lucy

2011, Höpflinger, François, Bayer-Oglesby, Lucy, Zumbrunn, Andrea

Buchreihe des Schweizerischen Gesundheitsobservatoriums

2009, Schindler, Christian, Keidel, Dirk, Gerbase, Margaret W., Zemp, Elisabeth, Bettschart, Robert, Brändli, Otto, Brutsche, Martin H., Burdet, Luc, Karrer, Werner, Knöpfli, Bruno, Pons, Marco, Rapp, Regula, Bayer-Oglesby, Lucy, Künzli, Nino, Schwartz, Joel, Liu, Lee-Jane S., Ackermann-Liebrich, Ursula, Rochat, Thierry

Rationale: Reductions in mortality following improvements in air quality were documented by several studies, and our group found, in an earlier analysis, that decreasing particulate levels attenuate lung function decline in adults. Objectives: We investigated whether decreases in particulates with an aerodynamic diameter of less than 10 microm (PM10) were associated with lower rates of reporting respiratory symptoms (i.e., decreased morbidity) on follow-up. Methods: The present analysis includes 7,019 subjects who underwent detailed baseline examinations in 1991 and a follow-up interview in 2002. Each subject was assigned model-based estimates of average PM10 during the 12 months preceding each health assessment and the difference was used as the exposure variable of interest (DeltaPM10). Analyses were stratified by symptom status at baseline and associations between DeltaPM10 and change in symptom status during follow-up were adjusted for important baseline characteristics, smoking status at follow-up, and season. We then estimated adjusted odds ratios for symptoms at follow-up and numbers of symptomatic cases prevented due to the observed reductions in PM10. Measurements and main results: Residential exposure to PM10 was lower in 2002 than in 1991 (mean decline 6.2 microg/m3; SD = 3.9 microg/m3). Estimated benefits (per 10,000 persons) attributable to the observed changes in PM10-levels were: 259 (95% confidence interval [CI]: 102-416) fewer subjects with regular cough, 179 (95% CI, 30-328) fewer subjects with chronic cough or phlegm and 137 (95% CI, 9-266) fewer subjects with wheezing and breathlessness. Conclusions: Reductions in particle levels in Switzerland over the 11-year follow-up period had a beneficial effect on respiratory symptoms among adults.

2015-04-30T00:00:00Z, Bayer-Oglesby, Lucy, Nieuwenboom, Jan Willem, Frey, Peter, Schmid, Holger

2012, Sally Liu, L.-J., Tsai, Ming-Yi, Keidel, Dirk, Gemperli, Armin, Ineichen, Alex, Hazenkamp-von Arx, Marianne, Bayer-Oglesby, Lucy, Rochat, Thierry, Künzli, Nino, Ackermann-Liebrich, Ursula, Straehl, Peter, Schwartz, Joel, Schindler, Christian

Although recent air pollution epidemiologic studies have embraced land-use regression models for estimating outdoor traffic exposure, few have examined the spatio-temporal variability of traffic related pollution over a long term period and the optimal methods to take these factors into account for exposure estimates. We used home outdoor NO2 measurements taken from eight geographically diverse areas to examine spatio-temporal variations, construct, and evaluate models that could best predict the within-city contrasts in observations. Passive NO2 measurements were taken outside of up to 100 residences per area over three seasons in 1993 and 2003 as part of the Swiss cohort study on air pollution and lung and heart disease in adults (SAPALDIA). The spatio-temporal variation of NO2 differed by area and year. Regression models constructed using the annual NO2 means from central monitoring stations and geographic parameters predicted home outdoor NO2 levels better than a dispersion model. However, both the regression and dispersion models underestimated the within-city contrasts of NO2 levels. Our results indicated that the best models should be constructed for individual areas and years, and would use the dispersion estimates as the urban background, geographic information system (GIS) parameters to enhance local characteristics, and temporal and meteorological variables to capture changing local dynamics. Such models would be powerful tools for assessing health effects from long-term exposure to air pollution in a large cohort

2010, Zumbrunn, Andrea, Bayer-Oglesby, Lucy, Kocher, Gerhard, Oggier, Willy

2015, Zumbrunn, Andrea, Bayer-Oglesby, Lucy, Oggier, Willy

2011-12-27, Bayer-Oglesby, Lucy, Künzli, Nino, Röösli, Martin, Braun-Fahrländer, Charlotte, Mathys, Patrick, Stern, Willem, Jantunen, Matti, Kousa, Anu

To evaluate the validity of fixed-site fine particle levels as exposure surrogates in air pollution epidemiology, we considered four indicator groups: (1) PM2.5 total mass concentrations, (2) sulfur and potassium for regional air pollution, (3) lead and bromine for traffic-related particles, and (4) calcium for crustal particles. Using data from the European EXPOLIS (Air Pollution Exposure Distribution within Adult Urban Populations in Europe) study, we assessed the associations between 48-hr personal exposures and home outdoor levels of the indicators. Furthermore, within-city variability of fine particle levels was evaluated. Personal exposures to PM2.5 mass were not correlated to corresponding home outdoor levels (n = 44, rSpearman (Sp) = 0.07). In the group reporting neither relevant indoor sources nor relevant activities, personal exposures and home outdoor levels of sulfur were highly correlated (n = 40, rSp = 0.85). In contrast, the associations were weaker for traffic (Pb: n = 44, rSp = 0.53; Br: n = 44, rSp = 0.21) and crustal (Ca: n = 44, rSp = 0.12) indicators. This contrast is consistent with spatially homogeneous regional pollution and higher spatial variability of traffic and crustal indicators observed in Basel, Switzerland. We conclude that for regional air pollution, fixed-site fine particle levels are valid exposure surrogates. For source-specific exposures, however, fixed-site data are probably not the optimal measure. Still, in air pollution epidemiology, ambient PM2.5 levels may be more appropriate exposure estimates than total personal PM2.5 exposure, since the latter reflects a mixture of indoor and outdoor sources.

2010, Zumbrunn, Andrea, Bayer-Oglesby, Lucy, Roth, Maik