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- PublikationRWD-Cockpit. Application for quality assessment of real-world data(JMIR Publications, 18.10.2022) Degen, Markus; Babrak, Lmar; Smakaj, Erand; Agac, Teyfik; Asprion, Petra; Grimberg, Frank; Van der Werf, Daan; Van Ginkel, Erwin Willem; Tosoni, Deniz David; Clay, Ieuan; Brodbeck, Dominique; Natali, Eriberto; Schkommodau, Erik; Miho, Enkelejda [in: JMIR Formative Research]Digital technologies are transforming the health care system. A large part of information is generated as real-world data (RWD). Data from electronic health records and digital biomarkers have the potential to reveal associations between the benefits and adverse events of medicines, establish new patient-stratification principles, expose unknown disease correlations, and inform on preventive measures. The impact for health care payers and providers, the biopharmaceutical industry, and governments is massive in terms of health outcomes, quality of care, and cost. However, a framework to assess the preliminary quality of RWD is missing, thus hindering the conduct of population-based observational studies to support regulatory decision-making and real-world evidence.01A - Beitrag in wissenschaftlicher Zeitschrift
- PublikationCloud-based three-dimensional pattern analysis and classification of proximal humeral fractures – A feasibility study(EasyChair, 2022) Kalt, Denise; Gerber Popp, Ariane; Degen, Markus; Brodbeck, Dominique; Coigny, Florian; Suter, Thomas; Schkommodau, Erik; Rodriguez y Baena, Ferdinando; Giles, Joshua W.; Stindel, Eric [in: Proceedings of the 20th Annual Meeting of the International Society for Computer Assisted Orthopaedic Surgery]For the complex clinical issue of treatment decision for proximal humeral fractures, dedicated software based on three-dimensional (3D) computer tomography (CT) models would potentially allow for a more accurate fracture classification and help to plan the surgical strategy needed to reduce the fracture in the operating theatre. The aim of this study was to elaborate the feasibility of implementation of such software using state-of-the-art cloud technology to enable access to its functionalities in a distributed manner. Feasibility was studied by implementation of a prototype application, which was tested in a usability study with five biomedical engineers. Implementation of a cloud-based solution was feasible using state-of-the-art technology under application of a specific software architectural approach allowing to distribute computational load between client and server. Mean System Usability Scale (SUS) Score for the developed application was determined to be 63 (StDev 20.4). These results can be interpreted as a medium low usability with high standard deviation of the measured SUS score. We conclude that more test subjects should be included in future studies and the developed application should be evaluated with a representative user group such as orthopaedic shoulder surgeons in a clinical setting.04B - Beitrag Konferenzschrift
- PublikationThe energy consumption of radiology. Energy- and cost-saving opportunities for CT and MRI operation(Radiological Society of North America, 24.03.2020) Heye, Tobias; Knoerl, Roland; Wehrle, Thomas; Mangold, Daniel; Cerminara, Alessandro; Loser, Michael; Plumeyer, Martin; Merkle, Elmar; Degen, Markus; Lüthy, Rahel; Brodbeck, Dominique [in: Radiology]Background Awareness of energy efficiency has been rising in the industrial and residential sectors but only recently in the health care sector. Purpose To measure the energy consumption of modern CT and MRI scanners in a university hospital radiology department and to estimate energy- and cost-saving potential during clinical operation. Materials and Methods Three CT scanners, four MRI scanners, and cooling systems were equipped with kilowatt-hour energy measurement sensors (2-Hz sampling rate). Energy measurements, the scanners’ log files, and the radiology information system from the entire year 2015 were analyzed and segmented into scan modes, as follows: net scan (actual imaging), active (room time), idle, and system-on and system-off states (no standby mode was available). Per-examination and peak energy consumption were calculated. Results The aggregated energy consumption imaging 40 276 patients amounted to 614 825 kWh, dedicated cooling systems to 492 624 kWh, representing 44.5% of the combined consumption of 1 107 450 kWh (at a cost of U.S. $199 341). This is equivalent to the usage in a town of 852 people and constituted 4.0% of the total yearly energy consumption at the authors' hospital. Mean consumption per CT examination over 1 year was 1.2 kWh, with a mean energy cost (±standard deviation) of $0.22 ± 0.13. The total energy consumption of one CT scanner for 1 year was 26 226 kWh ($4721 in energy cost). The net consumption per CT examination over 1 year was 3580 kWh, which is comparable to the usage of a two-person household in Switzerland; however, idle state consumption was fourfold that of net consumption (14 289 kWh). Mean MRI consumption over 1 year was 19.9 kWh per examination, with a mean energy cost of $3.57 ± 0.96. The mean consumption for a year in the system-on state was 82 174 kWh per MRI examination and 134 037 kWh for total consumption, for an energy cost of $24 127. Conclusion CT and MRI energy consumption is substantial. Considerable energy- and cost-saving potential is present during nonproductive idle and system-off modes, and this realization could decrease total cost of ownership while increasing energy efficiency.01A - Beitrag in wissenschaftlicher Zeitschrift