Hradetzky, David

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David
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Hradetzky, David

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20131
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Autor:in: Geiser, Thomas × Thema: Bronchoscopy ×

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    Publikation
    Design of miniaturized electro spray instrument for gene and drug therapeutic treatment of IPF
    (De Gruyter, 2013) Fiave, Prosper Agbesi; Boehringer, Stephan; Gazdhar, Amiq; Geiser, Thomas; Hradetzky, David [in: Biomedical Engineering / Biomedizinische Technik]
    Electric field accelerated plasmid droplets to permeate tissues has been demonstrated on cell culture and ex-vivo lung tissue of rats using enhanced green fluorescence protein reporter gene for transfection. This opens a window of opportunity to design an electrospray instrument usable within the working channel of bronchoscope to noninvasively treat idiopathic pulmonary fibrosis (IPF). We elaborate a concept and realized a device usable in the working channel of a flexible bronchoscope taking into account restrictions within typical bronchoscopy procedure.
    01A - Beitrag in wissenschaftlicher Zeitschrift