Hradetzky, David

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Hradetzky
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David
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Hradetzky, David

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20211
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Autor:in: Ruzgys, Paulius × Thema: Coulomb repulsion ×

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    Publikation
    Electrospray mediated localized and targeted chemotherapy in a mouse model of lung cancer
    (Frontiers, 21.04.2021) Hradetzky, David; Gazdhar, Amiq; Ruzgys, Paulius; Böhringer, Stephan; Sila Dokumaci, Ayse; Hari, Yvonne; Schürch, Christian; Brühl, Frido; Schürch, Stefan; Sönke, Szidat; Riether, Carsten; Satkauskas, Saulius; Geiser, Thomas [in: Frontiers in Pharmacology]
    An advanced stage, centrally localized invasive tumor is a major cause of sudden death in lung cancer patients. Currently, chemotherapy, radiotherapy, laser ablation, or surgical resection if possible are the available state-of-the-art treatments but none of these guarantee remedy or long-term relief and are often associated with fatal complications. Allowing localized chemotherapy, by direct and confined drug delivery only at the tumor site, could be a promising option for preoperative down staging or palliative therapy. Here we report the localized and targeted application of intra tumor delivery of chemotherapeutics using a novel device based on the principle of electrospray.
    01A - Beitrag in wissenschaftlicher Zeitschrift