An Acute Ocfentanil Fatality: A Case Report with Postmortem Concentrations

dc.accessRightsAnonymous
dc.audienceScience
dc.contributor.authorDussy, Franz
dc.contributor.authorHangartner, Sarah
dc.contributor.authorHamberg, Cornelia
dc.contributor.authorBerchtold, Christoph
dc.contributor.authorScherer, Ulrich
dc.contributor.authorSchlotterbeck, Götz
dc.contributor.authorWyler, David
dc.contributor.authorBriellmann, Thomas
dc.date.accessioned2016-12-07T11:14:08Z
dc.date.available2016-12-07T11:14:08Z
dc.date.issued2016
dc.description.abstractA 24-year-old man known to consume illegal drugs was found dead in his apartment. A reclosable plastic zipper bag containing several hundred milligrams of a brown powder was found close to the dead body and the first assumption of the investigators was death due to heroin intoxication. Therefore, a legal autopsy was ordered. The following toxicological analysis revealed ocfentanil in urine and in the brown powder. Four different approaches for the determination of the ocfentanil concentrations in peripheral whole blood are described. Enrichment of ocfentanil from the powder was realized. With this reference, it was possible to determine the ocfentanil concentration in the seized powder to be 0.91%. Concentrations of ocfentanil were also determined in the sampled body fluids using the standard addition procedure. In peripheral blood 9.1 µg/L, in heart blood 27.9 µg/L and in urine 480 µg/L were measured. In addition, the antidepressant citalopram, the neuroleptic quetiapine and cannabinoids were found in urine and subsequently quantified in peripheral blood.
dc.description.urihttps://academic.oup.com/jat/article-abstract/40/9/761/2527453/An-Acute-Ocfentanil-Fatality-A-Case-Report-with?redirectedFrom=fulltext
dc.identifier.doihttps://doi.org/10.1093/jat/bkw096
dc.identifier.issn1945-2403
dc.identifier.issn0146-4760
dc.identifier.urihttp://hdl.handle.net/11654/23644
dc.issue9
dc.language.isoenen_US
dc.publisherOxford University Pressen_US
dc.relation.ispartofJournal of Analytical Toxicologyen_US
dc.titleAn Acute Ocfentanil Fatality: A Case Report with Postmortem Concentrations
dc.type01A - Beitrag in wissenschaftlicher Zeitschrift
dc.volume40
dspace.entity.typePublication
fhnw.InventedHereYes
fhnw.IsStudentsWorkno
fhnw.PublishedSwitzerlandNo
fhnw.ReviewTypeAnonymous ex ante peer review of a complete publication
fhnw.affiliation.hochschuleHochschule für Life Sciencesde_CH
fhnw.affiliation.institutInstitut für Chemie und Bioanalytikde_CH
fhnw.pagination761-766
fhnw.publicationOnlineJa
fhnw.publicationStatePre-Print
relation.isAuthorOfPublication0bd5de70-5b10-46bf-aaf3-eb79c4eb10be
relation.isAuthorOfPublication.latestForDiscovery0bd5de70-5b10-46bf-aaf3-eb79c4eb10be
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