Biomimetic Remineralization of Carious Lesions by Self-Assembling Peptide

Loading...
Thumbnail Image
Files
[Biomimetic Remineralization of Carious Lesions by Self-Assembling Peptide_Lucy Kind]
Authors
Kind, Lucy
Stevanovic, Sabrina
Wuttig, Sina
Wimberger, Sandra
Hofer, Joëlle
Müller, Bert
Author (Corporation)
Publication date
27.03.2017
Typ of student thesis
Course of study
Type
01A - Journal article
Editors
Editor (Corporation)
Supervisor
Parent work
Journal of Dental Research
Special issue
DOI of the original publication
Link
Series
Series number
Volume
Issue / Number
Pages / Duration
1-8
Patent number
Publisher / Publishing institution
SAGE
Place of publication / Event location
Edition
Version
Programming language
Assignee
Practice partner / Client
Abstract
Self-assembling β-sheet forming peptide P11-4 has shown potential in the treatment and prevention of dental caries by supporting tissue regeneration. It has previously been shown that application of monomeric P11-4 solution to early carious lesions can increase net mineral gain by forming de novo hydroxyapatite crystals. The hypothesis for the mode of action was that monomeric self-assembling peptide P11-4 diffuses into the subsurface lesion body and assembles therein into higher order fibrils, facilitating mineralization of the subsurface volume by mimicking the natural biomineralization of the tooth enamel.
Keywords
enamel biomineralization/formation, micro–computed tomography, regeneration, scanning electron microscopy (SEM), dentistry
Subject (DDC)
Project
Event
Exhibition start date
Exhibition end date
Conference start date
Conference end date
Date of the last check
ISBN
ISSN
0022-0345
1544-0591
Language
English
Created during FHNW affiliation
Yes
Strategic action fields FHNW
Publication status
Published
Review
Expert editing/editorial review
Open access category
License
Citation
Kind, L., Stevanovic, S., Wuttig, S., Wimberger, S., Hofer, J., Müller, B., & Pieles, U. (2017). Biomimetic Remineralization of Carious Lesions by Self-Assembling Peptide. Journal of Dental Research, 1–8. https://doi.org/10.1177/0022034517698419