Ibervillea sonorae (S. Watson) Green a potential resource of bioactive compounds: Systematic analysis of a Mexican plant used in traditional medicine
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Author (Corporation)
Publication date
2025
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04A - Book part
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Studies in Natural Products Chemistry
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DOI of the original publication
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Volume
85
Issue / Number
Pages / Duration
395-443
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Publisher / Publishing institution
Elsevier
Place of publication / Event location
Amsterdam
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Abstract
Ibervillea sonorae (S. Watson) Green (Cucurbitaceae) is a tuber succulent known as “wareke,” which grows in dry desert landscapes in northwestern Mexico and the southwestern United States. Indigenous tribes use I. sonorae as a remedy against cancer, inflammation, rheumatism, skin infections, and diabetes. The great popularity of wareke in traditional medicine has motivated various working groups to investigate its pharmacological properties. The antiproliferative, antitumoral, antifungal, hypoglycemic, antiinflammatory, antioxidant, and antimicrobial potential of this plant has been established. Chemical studies showed that I. sonorae is a potential resource of bioactive compounds, cucurbitacin-type triterpenoids, and phytosterols, the main secondary metabolites. The objective of this chapter is to systematically analyze the phytochemical knowledge of the plant (isolated and identified compounds), describe the biological activities of different extracts, isolated ingredients, and phytopreparations, and discuss their possible applications.
Keywords
Cancer, Cucurbitacin IIb, Cucurbitacins, Diabetes, Ibervillea sonorae, Kinoin A, Mexican plant, Phytosterols, Traditional medicine, Triterpenes
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ISBN
978-0-443-23754-6
978-0-443-23755-3
978-0-443-23755-3
ISSN
1572-5995
Language
English
Created during FHNW affiliation
Yes
Strategic action fields FHNW
Publication status
Published
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Expert editing/editorial review
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Closed
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Citation
Molina, A. A., Di Cristofaro, V., Pieles, U., Romero, J. C. L., Gutiérrez, M. V., Gutiérrez, S. H., Zepeda, R. E. R., & Moreno, H. T. (2025). Ibervillea sonorae (S. Watson) Green a potential resource of bioactive compounds: Systematic analysis of a Mexican plant used in traditional medicine. In Atta-ur-Rahman & International Center for Chemical and Biological Sciences (Eds.), Studies in Natural Products Chemistry (Vol. 85, pp. 395–443). Elsevier. https://doi.org/10.1016/b978-0-443-23754-6.00017-3