Ibervillea sonorae (S. Watson) Green a potential resource of bioactive compounds: Systematic analysis of a Mexican plant used in traditional medicine

Ibervillea sonorae (S. Watson) Green (Cucurbitaceae) is a tuber succulent known as “wareke,” which grows in dry desert landscapes in northwestern Mexico and the southwestern United States. Indigenous tribes use I. sonorae as a remedy against cancer, inflammation, rheumatism, skin infections, and diabetes. The great popularity of wareke in traditional medicine has motivated various working groups to investigate its pharmacological properties. The antiproliferative, antitumoral, antifungal, hypoglycemic, antiinflammatory, antioxidant, and antimicrobial potential of this plant has been established. Chemical studies showed that I. sonorae is a potential resource of bioactive compounds, cucurbitacin-type triterpenoids, and phytosterols, the main secondary metabolites. The objective of this chapter is to systematically analyze the phytochemical knowledge of the plant (isolated and identified compounds), describe the biological activities of different extracts, isolated ingredients, and phytopreparations, and discuss their possible applications.

Schlagwörter

Cancer, Cucurbitacin IIb, Cucurbitacins, Diabetes, Ibervillea sonorae, Kinoin A, Mexican plant, Phytosterols, Traditional medicine, Triterpenes

Fachgebiet (DDC)

Projekt

Veranstaltung

Startdatum der Ausstellung

Enddatum der Ausstellung

Startdatum der Konferenz

Enddatum der Konferenz

Datum der letzten Prüfung

ISBN

978-0-443-23754-6
978-0-443-23755-3

ISSN

1572-5995

Sprache

Englisch

Während FHNW Zugehörigkeit erstellt

Ja

Zukunftsfelder FHNW

Publikationsstatus

Veröffentlicht

Begutachtung

Fachlektorat/Editorial Review

Open Access-Status

Closed

Lizenz

Zitation

Molina, A. A., Di Cristofaro, V., Pieles, U., Romero, J. C. L., Gutiérrez, M. V., Gutiérrez, S. H., Zepeda, R. E. R., & Moreno, H. T. (2025). Ibervillea sonorae (S. Watson) Green a potential resource of bioactive compounds: Systematic analysis of a Mexican plant used in traditional medicine. In Atta-ur-Rahman & International Center for Chemical and Biological Sciences (Eds.), Studies in Natural Products Chemistry (Vol. 85, pp. 395–443). Elsevier. https://doi.org/10.1016/b978-0-443-23754-6.00017-3

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