Label free detection of biomolecular interactions

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dc.contributor.authorHradetzky, David
dc.contributor.authorMüller, Claas
dc.contributor.authorReinecke, Holger
dc.date.accessioned2024-08-13T07:42:40Z
dc.date.available2024-08-13T07:42:40Z
dc.date.issued2005
dc.description.abstractThis work presents a simple evanescent wave sensing system based on an interferometric approach suitable to meet the demands on label free sensor systems for the detection of biomolecular interactions especially. It is representing a basic concept towards high throughput application. The system performance and reproducibility was evaluated with refractometric measurements of sucrose dilutions. A mean resolution of the effective refractive index of 3sigma(Deltamacrnmacr eff )=0.9middot10 -6 without averaging and a reproducibility below sigma r =0.1middot10 -6 were achieved. The suitability for the detection of biomolecular interactions was validated with the detection of a DNA hybridization
dc.eventIEEE/LEOS International Conference on Optical MEMS and Their Applications Conference
dc.event.end2005-08-04
dc.event.start2005-08-01
dc.identifier.doi10.1109/omems.2005.1540087
dc.identifier.isbn0-7803-9278-7
dc.identifier.isbn2160-5033
dc.identifier.isbn2160-5041
dc.identifier.urihttps://irf.fhnw.ch/handle/11654/46769
dc.language.isoen
dc.publisherIEEE
dc.relation.ispartofIEEE/LEOS International Conference on Optical MEMS and Their Applications Conference, 2005.
dc.spatialOulu
dc.subject.ddc600 - Technik, Medizin, angewandte Wissenschaften
dc.titleLabel free detection of biomolecular interactions
dc.type04B - Beitrag Konferenzschrift
dspace.entity.typePublication
fhnw.InventedHereNo
fhnw.ReviewTypeAnonymous ex ante peer review of a complete publication
fhnw.affiliation.hochschuleHochschule für Life Sciencesde_CH
fhnw.affiliation.institutInstitut für Medizintechnik und Medizininformatikde_CH
fhnw.openAccessCategoryClosed
fhnw.pagination81-82
fhnw.publicationStatePublished
relation.isAuthorOfPublicationc9dfc5bf-b9cd-4a1b-b606-eee6c639fd56
relation.isAuthorOfPublication.latestForDiscoveryc9dfc5bf-b9cd-4a1b-b606-eee6c639fd56
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