An Acute Ocfentanil Fatality: A Case Report with Postmortem Concentrations
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Autor:innen
Dussy, Franz
Hangartner, Sarah
Hamberg, Cornelia
Berchtold, Christoph
Scherer, Ulrich
Wyler, David
Briellmann, Thomas
Autor:in (Körperschaft)
Publikationsdatum
2016
Typ der Arbeit
Studiengang
Typ
01A - Beitrag in wissenschaftlicher Zeitschrift
Herausgeber:innen
Herausgeber:in (Körperschaft)
Betreuer:in
Ãœbergeordnetes Werk
Journal of Analytical Toxicology
Themenheft
Reihe / Serie
Jahrgang / Band
40
Ausgabe / Nummer
9
Seiten / Dauer
761-766
Patentnummer
Verlag / Herausgebende Institution
Oxford University Press
Verlagsort / Veranstaltungsort
Auflage
Version
Programmiersprache
Abtretungsempfänger:in
Praxispartner:in/Auftraggeber:in
Zusammenfassung
A 24-year-old man known to consume illegal drugs was found dead in his apartment. A reclosable plastic zipper bag containing several hundred milligrams of a brown powder was found close to the dead body and the first assumption of the investigators was death due to heroin intoxication. Therefore, a legal autopsy was ordered. The following toxicological analysis revealed ocfentanil in urine and in the brown powder. Four different approaches for the determination of the ocfentanil concentrations in peripheral whole blood are described. Enrichment of ocfentanil from the powder was realized. With this reference, it was possible to determine the ocfentanil concentration in the seized powder to be 0.91%. Concentrations of ocfentanil were also determined in the sampled body fluids using the standard addition procedure. In peripheral blood 9.1 µg/L, in heart blood 27.9 µg/L and in urine 480 µg/L were measured. In addition, the antidepressant citalopram, the neuroleptic quetiapine and cannabinoids were found in urine and subsequently quantified in peripheral blood.
Schlagwörter
Fachgebiet (DDC)
Veranstaltung
Startdatum der Ausstellung
Enddatum der Ausstellung
Startdatum der Konferenz
Enddatum der Konferenz
Datum der letzten Prüfung
ISBN
ISSN
1945-2403
0146-4760
0146-4760
Sprache
Englisch
Während FHNW Zugehörigkeit erstellt
Ja
Publikationsstatus
Preprint
Begutachtung
Peer-Review der ganzen Publikation
Open Access-Status
Lizenz
Zitation
DUSSY, Franz, Sarah HANGARTNER, Cornelia HAMBERG, Christoph BERCHTOLD, Ulrich SCHERER, Götz SCHLOTTERBECK, David WYLER und Thomas BRIELLMANN, 2016. An Acute Ocfentanil Fatality: A Case Report with Postmortem Concentrations. Journal of Analytical Toxicology. 2016. Bd. 40, Nr. 9, S. 761–766. DOI /10.1093/jat/bkw096. Verfügbar unter: http://hdl.handle.net/11654/23644