Isolation and characterization of pancreatic lipase inhibitor from rapeseed seeds
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Autor:innen
Krusir, Galyna
Pylypenko, Liudmyla
Sevastyanova, Elena
Mazurenko, Kseniia
Moshtakov, Serhii
Shunko, Hanna
Vitiuk, Antonina
Shpyrko, Tetyana
Autor:in (Körperschaft)
Publikationsdatum
2023
Typ der Arbeit
Studiengang
Sammlung
Typ
01A - Beitrag in wissenschaftlicher Zeitschrift
Herausgeber:innen
Herausgeber:in (Körperschaft)
Betreuer:in
Übergeordnetes Werk
Journal of Chemistry and Technologies
Themenheft
DOI der Originalpublikation
Link
Reihe / Serie
Reihennummer
Jahrgang / Band
31
Ausgabe / Nummer
2
Seiten / Dauer
255-270
Patentnummer
Verlag / Herausgebende Institution
Oles Honchar Dnipro National University
Verlagsort / Veranstaltungsort
Auflage
Version
Programmiersprache
Abtretungsempfänger:in
Praxispartner:in/Auftraggeber:in
Zusammenfassung
Digestive enzymes and inhibitors of digestive enzymes are effective correctors of digestive processes in the body, the violation of which leads to various diseases (diabetes, hyperlipidemia, cardiovascular diseases, neoplasms and others). The present study identified the most promising plant objects characterized by the highest antilipolytic activity (ALA) in relation to pancreatic lipase. The experimental results indicate that the inhibitory activity (IA) of phenolic compounds of rapeseed is so much high and comparable to ALA "Orlistat", reaching 95.5 % of its activity. This determines the potential possibility of using the phenolic complex of rapeseed as an alternative to anti-lipolytic drugs of synthetic origin. The predominant component of the phenolic complex is low molecular weight phenolic compounds; polyphenolic compounds are almost equally represented by tannins – condensed and hydrolyzable. According to TLC data, the main components of low molecular weight phenols are glucopyranosylsinapate, sinapic acid and sinapin. Among the phenolic compounds of rapeseed seeds, sinapine and hydrolyzable tannins have the highest anti lipolytic activity against lipase. Significant ability to inhibit the action of pancreatic lipase is characterized by both low molecular weight and high molecular weight phenolic compounds of rapeseed.
Schlagwörter
Fachgebiet (DDC)
500 - Naturwissenschaften und Mathematik
Veranstaltung
Startdatum der Ausstellung
Enddatum der Ausstellung
Startdatum der Konferenz
Enddatum der Konferenz
Datum der letzten Prüfung
ISBN
ISSN
2663-2934
2663-2942
2663-2942
Sprache
Andere
Während FHNW Zugehörigkeit erstellt
Ja
Zukunftsfelder FHNW
Publikationsstatus
Veröffentlicht
Begutachtung
Peer-Review der ganzen Publikation
Open Access-Status
Gold
Lizenz
Zitation
KRUSIR, Galyna, Liudmyla PYLYPENKO, Elena SEVASTYANOVA, Kseniia MAZURENKO, Serhii MOSHTAKOV, Hanna SHUNKO, Antonina VITIUK, Tetyana SHPYRKO und Oleksandr ZDORYK, 2023. Isolation and characterization of pancreatic lipase inhibitor from rapeseed seeds. Journal of Chemistry and Technologies. 2023. Bd. 31, Nr. 2, S. 255–270. DOI 10.15421/jchemtech.v31i2.279214. Verfügbar unter: https://doi.org/10.26041/fhnw-7957