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Interferometric label-free biomolecular detection system
(IOP Publishing Ltd, 2006) Hradetzky, David; Mueller, Claas; Reinecke, Holger
This work presents a simple evanescent wave sensing system based on an interferometric approach, suitable to meet the requirements of label-free sensor systems for detecting biomolecular interactions. It represents a basic concept towards label-free detection systems in various applications. The basic objectives of transducers for evanescent wave sensing are discussed. An optical detection system based on a interferometric approach using Young's double slit configuration is discussed, set-up and characterized. With refractometric measurements of various sucrose dilutions, the performance of the pure optical set-up is evaluated.
01A - Beitrag in wissenschaftlicher Zeitschrift