Hochschule für Life Sciences FHNW

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Bereich: Suchergebnisse

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    Publikation
    Biomimetic Remineralization of Carious Lesions by Self-Assembling Peptide
    (SAGE, 27.03.2017) Kind, Lucy; Stevanovic, Sabrina; Wuttig, Sina; Wimberger, Sandra; Hofer, Joëlle; Müller, Bert; Pieles, Uwe
    Self-assembling β-sheet forming peptide P11-4 has shown potential in the treatment and prevention of dental caries by supporting tissue regeneration. It has previously been shown that application of monomeric P11-4 solution to early carious lesions can increase net mineral gain by forming de novo hydroxyapatite crystals. The hypothesis for the mode of action was that monomeric self-assembling peptide P11-4 diffuses into the subsurface lesion body and assembles therein into higher order fibrils, facilitating mineralization of the subsurface volume by mimicking the natural biomineralization of the tooth enamel.
    01A - Beitrag in wissenschaftlicher Zeitschrift