Hochschule für Life Sciences FHNW

Dauerhafte URI für den Bereichhttps://irf.fhnw.ch/handle/11654/22

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2015 - 201962020 - 202418

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Enddatum: 2024Thema: search.filters.subject.610 - Medizin und Gesundheit

Bereich: Suchergebnisse

Gerade angezeigt 1 - 10 von 24
  • Vorschaubild
    Publikation
    Microstructures, phase and mechanical characterisation of Al2O3-ZrO2-TiO2 coating produced by atmospheric plasma spraying
    (Elsevier, 20.12.2024) Chang, Cynthia Sin Ting; Wyss, Marcus; Andrzejewski, Michal; Darut, Geoffrey; Graf, Lukas; Novak, Vladimir; Olbinado, Margie; Erpel, Susanne; Vogel, Alexander; Bode, Simon; de Wild, Michael; Salito, Armando
    The microstructure, crystallographic phases, and mechanical properties of a newly developed Al2O3 – TiO2 – ZrO2 ternary ceramic coating were characterized. The coatings were produced by atmospheric plasma spraying as a preblended powder on Ti-6Al-4 V substrates using the new generation of the Debye-Larmor cascaded plasma torch. The 400 μm thick as-sprayed ternary ceramic coating is compact and neither delamination nor inter-/trans-granular cracks were found. The coating consists of single phase α-Al2O3, monoclinic m-ZrO2, and a nanocrystalline dual phase structure of α-Al2O3 and m-ZrO2. Ti is either present as ZrTiO4 or as solute in the dual phase. Cracking from the tip of the indent is rare and delamination was not observed after the progressive scratch test. The coating has potential in high wear applications for example in medical devices.
    01A - Beitrag in wissenschaftlicher Zeitschrift
  • Vorschaubild
    Publikation
    Evaluierung von Carbonatpuffer für die Wirkstofffreisetzung aus Tabletten
    (Hochschule für Life Sciences FHNW, 2024) Loureiro Cunha, Margarida; Lanz, Michael; Imanidis, Georgios
    11 - Studentische Arbeit
  • Vorschaubild
    Publikation
    Miniaturization of stent prototypes by µSLM
    (Hochschule für Life Sciences FHNW, 2024) Wasmer, Larissa; de Wild, Michael; Seiler, Daniel; Politecnico di Torino
    11 - Studentische Arbeit
  • Vorschaubild
    Publikation
    Atlas-Based Segmentation Algorithm
    (Hochschule für Life Sciences FHNW, 2024) Kohler, Roger; Vogel, Dorian; Linköpings Universitet
    11 - Studentische Arbeit
  • Vorschaubild
    Publikation
    Quantitative assessment of repetitive lower limb movements used in the MDS-UPDRS-III scale in healthy subjects
    (Hochschule für Life Sciences FHNW, 2024) Hunziker, Sven; Hemm-Ode, Simone; Vogel, Dorian; Kalt, Denise; Kantonsspital Baden AG, Baden AG
    11 - Studentische Arbeit
  • Vorschaubild
    Publikation
    Robustness comparison of optimization techniques in Intensity Modulated Proton Therapy (IMPT)
    (Hochschule für Life Sciences FHNW, 2024) Hagmann, Virgile; Knopf, Antje; Paul Scherrer Institut, Villigen
    11 - Studentische Arbeit
  • Vorschaubild
    Publikation
    Stimmanalyse zur Evaluierung des Leidens bei Patienten mit Krebs
    (Hochschule für Life Sciences FHNW, 2024) Dere, Türkmen; Hemm-Ode, Simone; Kantonsspital Baselland, Liestal; Palliativzentrum Hildegard, Basel
    11 - Studentische Arbeit
  • Vorschaubild
    Publikation
    Analysis of Patient Reported Outcome Measures (PROMs)
    (Hochschule für Life Sciences FHNW, 2024) Schlumpf, Oliver; Kahraman, Abdullah; Luzerner Kantonsspital (LUKS); Swiss Sarcoma Network (SSN)
    11 - Studentische Arbeit
  • Vorschaubild
    Publikation
    Investigation of different quality assessment procedures for fast and reliable validation of CBCT-based synthetic CTs
    (Hochschule für Life Sciences FHNW, 2024) Maurenbrecher, Joakim; Knopf, Antje; Paul Scherrer Institut, Villigen
    11 - Studentische Arbeit
  • Vorschaubild
    Publikation
    Maturation of the human immunoglobulin heavy chain repertoire with age
    (Frontiers Research Foundation, 06.08.2020) Ghraichy, Marie; Galson, Jacob D.; Kovaltsuk, Aleksandr; von Niederhäusern, Valentin; Pachlopnik Schmid, Jana; Recher, Mike; Jauch, Annaïse J.; Miho, Enkelejda; Kelly, Dominic F.; Deane, Charlotte M.; Trück, Johannes
    B cells play a central role in adaptive immune processes, mainly through the production of antibodies. The maturation of the B cell system with age is poorly studied. We extensively investigated age-related alterations of naïve and antigen-experienced immunoglobulin heavy chain (IgH) repertoires. The most significant changes were observed in the first 10 years of life, and were characterized by altered immunoglobulin gene usage and an increased frequency of mutated antibodies structurally diverging from their germline precursors. Older age was associated with an increased usage of downstream IgH constant region genes and fewer antibodies with self-reactive properties. As mutations accumulated with age, the frequency of germline-encoded self-reactive antibodies decreased, indicating a possible beneficial role of self-reactive B cells in the developing immune system. Our results suggest a continuous process of change through childhood across a broad range of parameters characterizing IgH repertoires and stress the importance of using well-selected, age-appropriate controls in IgH studies.
    01A - Beitrag in wissenschaftlicher Zeitschrift