de Wild, Michael
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Three anchor concepts for rotator cuff repair in standardized physiological and osteoporotic bone: a biomechanical study
2019-10-06, de Wild, Michael, Dietschy, Alain, Claudio, Rosso, Rosso, Claudio
The new LassoLoop360° technique for biomechanically superior tissue grip
2019, Müller, Sebastian, de Wild, Michael
PurposeSuprapectoral tenodesis is a frequently used technique for treating pathologies of the long head of the biceps bra-chii (LHBB) tendon. However, so far, no Gold Standard treatment exist. Hence, the arthroscopic LassoLoop360 (LL360) technique is introduced aiming to provide secure fixation and improved biomechanical properties. It was hypothesized, that the LL360 technique would show superior biomechanical response to cyclic loading and ultimate load-to-failure testing compared to the commonly used simple Lasso Loop (SLL).MethodsTwenty-two porcine superficial flexor digitorum tendons were prepared using a No. 2 suture according to either the SLL or the LL360 technique. Displacement after cyclic loading (1.000 cycles) between 5 and 30 N, ultimate load-to-failure (ULTF), mode of failure as well as the construct stiffness were tested.ResultsSignificantly less displacement was found in the LL360 group (SLL 2.25 ± 0.51 mm; LL360 1.67 ± 0.37 mm; p = 0.01). Ultimate Load to Failure was significantly higher in the LL360 (168.6 ± 29.6 N) as compared to the SLL (124.1 ± 25.8 N, p = 0.02). The LL360 also revealed a significant higher stiffness compared to the SLL (SLL 13.1 ± 0.9 N/mm vs. LL360 19.1 ± 1.0 N/mm, p < 0.001). The most common mode of failure was the suture cutting through the tendon, with a significantly less suture cutting through for the LL360 compared with the SLL (p < 0.05).ConclusionThe LassoLoop360-technique offers superior biomechanical characteristics regarding the tendon-suture-interface compared to the SLL. In the initial healing phase, the suture-tendon-interface is the most vulnerable part of the tendon-suture-anchor construct, the aim of this new technique is to reduce this weakest part of the chain (Ponce et al., Am J Sports Med 39:188–194, 2011). This technique may therefore be beneficial for arthroscopic suprapectoral biceps tenodesis at the entrance of the bicipital groove
Biomechanical comparison of Three Anchors for Rotator Cuff Repair in Standardized Physiological and Osteoporotic Bone - introducing 1000 loading cycles
2018-09, Müller, Stefan, Dietschy, Alain, de Wild, Michael, Rosso, Claudio, Weber, Timo
Osteoconductive Lattice Microarchitecture for Optimized Bone Regeneration
2018-06, de Wild, Michael, Ghayor, Chafik, Zimmermann, Simon, Rüegg, Jasmine, Nicholls, Flora, Schuler, Felix, Chen, Tse-Hsiang, Weber, Franz E.
Selective laser melting (SLM) is one methodology to realize additive manufacturing and is mainly used to join metal powder in a layer-by-layer manner to produce a solid three-dimensional (3D) object. For bone tissue engineering purposes, scaffolds can readily be designed as 3D data model and realized with titanium known for its excellent osseointegration behavior. The microarchitecture, that is, design with submillimeter features, of additively manufactured scaffolds is in many cases a lattice structure. This study aimed to apply SLM that allows a high degree of microarchitectural freedom to generate lattice structures and to determine the optimal distance between rods and the optimal diameter of rods for osteoconduction (bone ingrowth into scaffolds) and bone regeneration. For the biological readout, diverse SLM-fabricated titanium implants were placed in the calvarium of rabbits and new bone formation and defect bridging were determined after 4 weeks of healing. The results from the middle section of the defects show that with a lattice microarchitecture, the optimal distance between titanium rods is around 0.8 mm and the optimal rod dimension is between 0.3 and 0.4 mm to optimize defect bridging and bone regeneration.
Spirits – un projet Interreg / ein Interreg-Projekt
2019-04-05, de Wild, Michael, Renaud, Pierre
3D printing of titanium alloys for biomedical and robotic applications, Technical Day 2018, 3D Printing, Robotics and Medicine
2018-10, de Wild, Michael
Three Anchors For Rotator Cuff Repair Biomechanically Compared In Standardized Physiological And Osteoporotic Bone
2018-09, Rosso, Claudio, de Wild, Michael, Dietschy, Alain, Weber, Timo, Müller, Sebastian
Implant surface modification by a controlled biomimetic approach
2019-03-19, Carino, Agnese, de Wild, Michael, Dalcanale, Federico
Lattice Microarchitecture for Bone Tissue Engineering from Calcium Phosphate Compared to Titanium
2018-10, Chen, Tse-Hsiang, Ghayor, Chafik, Siegenthaler, Barbara, Schuler, Felix, Rüegg, Jasmine, de Wild, Michael, Weber, Franz E.
Additive manufacturing of bone tissue engineering scaffolds will become a key element for personalized bone tissue engineering in the near future. Several additive manufacturing processes are based on extrusion where the deposition of the filament will result in a three-dimensional lattice structure. Recently, we studied diverse lattice structures for bone tissue engineering realized by laser sintering of titanium. In this work, we used lithography-based ceramic manufacturing of lattice structures to produce scaffolds from tricalcium phosphates (TCP) and compared them in vivo to congruent titanium scaffolds manufactured with the identical computer-aided design data to look for material-based differences in bony healing. The results show that, during a 4-week period in a noncritical-size defect in a rabbit calvarium, both scaffolds with the identical microarchitecture performed equally well in terms of bony regeneration and bony bridging of the defect. A significant increase in both parameters could only be achieved when the TCP-based scaffolds were doped with bone morphogenetic protein-2. In a critical-size defect in the calvarial bone of rabbits, however, the titanium scaffold performed significantly better than the TCP-based scaffold, most likely due to its higher mechanical stability. We conclude that titanium and TCP-based scaffolds of the same microarchitecture perform equally well in terms of bone regeneration, provided the microarchitecture meets the mechanical demand at the site of implantation.
Development of a 3D biomechanical AC-joint model
2018-06, Sailer, Jannis, Bless, Nicolas, Dalcanale, Federico, Stürmer, Alexandra, Dietschy, Alain, de Wild, Michael, Müller, Andreas