Personal exposure assessment studies may suffer from exposure-relevant selection bias
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Authors
Rotko, Tuulia
Krütli, Pius
Boudet, Céline
Kruize, Hanneke
Jantunen, Matti
Künzli, Nino
Author (Corporation)
Publication date
27.07.2000
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01A - Journal article
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Parent work
Journal of Exposure Science & Environmental Epidemiology
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Volume
10
Issue / Number
3
Pages / Duration
251-266
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Abstract
We evaluated exposure-relevant selection bias within the framework of a study on personal air pollution exposure, using traffic data as exposure proxy. Based on random samples of 3000 (Basel) and 2532 (Helsinki) persons, 50 and 250 subjects, respectively, were recruited for direct monitoring and 250 (Basel, Helsinki) for indirect monitoring. In Basel, participants of direct monitoring as compared to non-participants were more likely to live at streets with low traffic volume (49% below 1st quartile vs. 27%). Adjusted for sex, age and nationality, an increase of 100 cars per hour was associated with 14% less participation (odds ratio (OR): 0.861; 95% CI: 0.731, 1.007). Although in Helsinki, traffic volume was neither significantly related to participation in direct nor indirect monitoring, the point estimates indicate a tendency to decreased participation with increasing traffic intensity at home. We conclude that selection bias regarding exposure-relevant characteristics is likely to occur when recruiting participants for studies including demanding personal exposure assessment. Correction for factors routinely collected may not fully account for exposure-relevant bias. This is of particular importance when using exposure data for modelling population exposure distributions, whereas in epidemiological studies, a reduced range of exposure must not a priori distort the exposure-response relationship.
Keywords
air pollutants, exposure assessment, non-respondents, risk assessment, selection bias, target population
Subject (DDC)
334 - Natürliche Ressourcen, Energie und Umwelt
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1559-0631
1559-064X
1559-064X
Language
English
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No
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Publication status
Published
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Peer review of the complete publication
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Citation
BAYER-OGLESBY, Lucy, Tuulia ROTKO, Pius KRÜTLI, Céline BOUDET, Hanneke KRUIZE, Matti JANTUNEN und Nino KÜNZLI, 2000. Personal exposure assessment studies may suffer from exposure-relevant selection bias. Journal of Exposure Science & Environmental Epidemiology. 27 Juli 2000. Bd. 10, Nr. 3, S. 251–266. DOI 10.1038/sj.jea.7500088. Verfügbar unter: https://irf.fhnw.ch/handle/11654/33497