Electrospray mediated localized and targeted chemotherapy in a mouse model of lung cancer
Type
01 - Zeitschriftenartikel, Journalartikel oder Magazin
Zusammenfassung
An advanced stage, centrally localized invasive tumor is a major cause of sudden death in lung cancer patients. Currently, chemotherapy, radiotherapy, laser ablation, or surgical resection if possible are the available state-of-the-art treatments but none of these guarantee remedy or long-term relief and are often associated with fatal complications. Allowing localized chemotherapy, by direct and confined drug delivery only at the tumor site, could be a promising option for preoperative down staging or palliative therapy. Here we report the localized and targeted application of intra tumor delivery of chemotherapeutics using a novel device based on the principle of electrospray.
DOI der Originalausgabe
https://doi.org/10.3389/fphar.2021.643492Übergeordnetes Werk
Frontiers in Pharmacology : Translational Pharmacology
Verlag / Hrsg. Institution
Frontiers
Zitation
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