Modeling-Based Approach Towards Quality by Design for a Telescoped Process

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Publikationsdatum
2022
Autor:innen
Zogg, Andreas
Zahnd, This
Zeitschriftentitel
ISSN der Zeitschrift
Bandtitel
Verlag
Hochschule für Life Sciences FHNW
Zusammenfassung
A synthesis step, consisting of two sub-steps A and B was investigated by applying a model based approach. Deepening the process understanding was achieved through performed experiments, which also led to the generation of valuable knowledge for future improvements. A kinetic model consisting of 12 reactions and 15 components was successfully established. The model predicts the effects of changes in process parameters on quality. On this basis recommendations for process optimizations have been formulated.
Beschreibung
Schlagwörter
Scale-Up / Scale-Down, Quality By Design (QBD), Process Modelling, Process Simulation, Reaction Kinetics
Zitierform
DOI der Originalpublikation
Zitation
ZOGG, Andreas und This ZAHND, 2022. Modeling-Based Approach Towards Quality by Design for a Telescoped Process. Muttenz: Hochschule für Life Sciences FHNW. Verfügbar unter: https://doi.org/10.26041/fhnw-4331

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2023-03-21 07:39:48
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2022-10-17 12:22:49
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