Institut für Chemie und Bioanalytik

Dauerhafte URI für die Sammlunghttps://irf.fhnw.ch/handle/11654/24

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2019 - 20202

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Thema: search.filters.subject.Process intensification

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  • Kein Vorschaubild vorhanden
    Publikation
    Integration of a liquid membrane in Taylor flow regime with a fermentation by Lactobacillus casei ATCC 393 for in-situ lactic acid removal
    (Elsevier, 06/2019) Pérez, Alan; Rodríguez-Barona, Sneyder; Fontalvo, Javier
    A new type of liquid membranes called liquid membrane in Taylor flow was integrated to a lactic acid fermentation, using Lactobacillus casei ATCC 393, for lactic acid removal during fermentation. The performance in terms of lactic acid production of the hybrid batch system is compared to a conventional batch fermentation. Lactic acid removal rate increases proportionally with the LA concentration within the fermenter. The lactic acid, the biomass production and the LA productivity in the hybrid system increased by 41.8, 12 and 26.6%, respectively, as compared to the conventional batch fermentation. However, toxicity effects reduce LA to glucose yield in 15.9% as compared to conventional fermentation. Liquid membranes in Taylor flow results promising for enhancing batch and continuous fermentation processes by a hybrid system.
    01A - Beitrag in wissenschaftlicher Zeitschrift
  • Kein Vorschaubild vorhanden
    Publikation
    In-situ recovery of carboxylic acids from fermentation broths through membrane supported reactive extraction using membrane modules with improved stability
    (Elsevier, 15.06.2020) Gössi, Angelo; Burgener, Florian; Kohler, David; Urso, Alessandro; Kolvenbach, Boris; Riedl, Wolfgang
    Membrane supported reactive extraction (MSE) coupled to back-extraction (MSBE) using a new type of Teflon (PTFE) capillary membrane contactor was studied for the in-situ removal of carboxylic acids from aqueous streams, e.g. fermentation broths. The use of microporous membranes as extraction interface helps avoiding emulsification problems, allows the use of extreme phase ratios, and protects microorganisms, as they are less affected by solvent toxicity during in-situ extractions. The use of PTFE capillary membranes is suitable for long-term use due its high chemical and thermal stability. A simple toxicity screening identified n-decanol with tri n-octyl amine (TOA) as a suitable solvent. MSE experiments were performed using membrane contactors (0.005 m2 to 0.15 m2), working with solvent to feed phase ratios down to 1:40 (mass based). The in-situ removal of lactic acid out of fermentation broths using lactobacillus plantarum led to a glucose conversion rate of 80 mol%. Additionally, a concentration factor up to 7.8 could be shown during back-extraction.
    01A - Beitrag in wissenschaftlicher Zeitschrift