Follow-up of the Swiss Cohort Study on Air Pollution and Lung Diseases in Adults (SAPALDIA 2) 1991–2003: methods and characterization of participants

Objectives: The Swiss Cohort Study on Air Pollution and Lung Diseases in Adults (SAPALDIA) was designed to investigate the health effects from long-term exposure to air pollution. Methods: The health assessment at recruitment (1991) and at the first reassessment (2001-3) consisted of an interview about respiratory health, occupational and other exposures, spirometry, a methacholine bronchial challenge test, end-expiratory carbon monoxide (CO) measurement and measurement for atopy. A bio bank for DNA and blood markers was established. Heart rate variability was measured using a 24-hour ECG (Holter) in a random sample of participants aged 50 years and older. Concentrations of nitrogen dioxide (NO2), sulphur dioxide (SO2), ozone (O3) and particulates in ambient air have been monitored in all study areas since 1991. Residential histories collected over the 11 year follow-up period coupled with GIS modelling will provide individual long-term air pollutant exposure estimates. Results: Of 9651 participants examined in 1991, 8715 could be traced for the cohort study and 283 died. Basic information about health status was obtained for 8047 individuals (86% of alive persons), 6 528 individuals (70%) agreed to the health examination and 5 973 subjects (62%) completed the entire protocol. Non-participants in the reassessment were on average younger than participants and more likely to have been smokers and to have reported respiratory symptoms in the first assessment. Average weight had increased by 5.5 kg in 11 years and 28% of smokers in 1991 had quit by the time of the reassessment.

Schlagwörter

Fachgebiet (DDC)

300 - Sozialwissenschaften, Soziologie, Anthropologie
610 - Medizin und Gesundheit

Projekt

Veranstaltung

Startdatum der Ausstellung

Enddatum der Ausstellung

Startdatum der Konferenz

Enddatum der Konferenz

Datum der letzten Prüfung

ISBN

ISSN

0303-8408
1420-911X

Sprache

Englisch

Während FHNW Zugehörigkeit erstellt

Nein

Zukunftsfelder FHNW

Publikationsstatus

Veröffentlicht

Begutachtung

Peer-Review der ganzen Publikation

Open Access-Status

Closed

Lizenz

Zitation

ACKERMANN-LIEBRICH, Ursula, Birgit KUNA-DIBBERT, Nicole M. PROBST-HENSCH, Christian SCHINDLER, Denise Felber DIETRICH, Elisabeth Zemp STUTZ, Lucy BAYER-OGLESBY, Felix BAUM, Otto BRÄNDLI, Martin BRUTSCHE, Sara H. DOWNS, Dirk KEIDEL, Margaret W. GERBASE, Medea IMBODEN, Roland KELLER, Bruno KNÖPFLI, Nino KÜNZLI, Laurent NICOD, Marco PONS, Patricia STAEDELE, Jean-Marie TSCHOPP, Jean-Pierre ZELLWEGER und Philippe LEUENBERGER, 2005. Follow-up of the Swiss Cohort Study on Air Pollution and Lung Diseases in Adults (SAPALDIA 2) 1991–2003: methods and characterization of participants. Sozial- und Präventivmedizin. 2005. Bd. 50, Nr. 4, S. 245–263. DOI 10.1007/s00038-005-4075-5. Verfügbar unter: https://irf.fhnw.ch/handle/11654/45648

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