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Projekt Projekt Projekt Publikation COVID-19 outbreak during inpatient rehabilitation(Wolters & Kluwer, 2021) Spielmanns, Marc; Pekacka-Egli, Anna Maria; Cecon, Mikis; Witassek, Fabienne; Schoendorf, Sabine; Lutz, Dietmar; Hermann, MatthiasObjective The COVID-19 pandemic affects a large number of patients. The impact on feasibility and outcome of rehabilitation during COVID-19 actually remains unclear. Nosocomial infection of healthcare workers or hospitalized patients is common, and prevention of nosocomial infections during rehabilitation is challenging. Therefore, we analyzed a cohort of nosocomial infected COVID-19 patients in a single-center inpatient rehabilitation clinic and described performance and outcome. Design The cohort describes patients with nosocomial SARS-CoV-2 infection while participating in neuromusculoskeletal rehabilitation. Infection was caused by an initially unidentified so-called superspreader. We compared this cohort with all neuromusculoskeletal rehabilitation inpatients of 2019 (comparison group). Normally distributed continuous variables were presented as mean with standard deviation and the test was used for comparison between groups. Linear regression was used to assess the impact of COVID-19 on Functional Independence Measure at discharge. Results COVID-19 patients were mostly male (66.7%) with an age of 71.5 ± 12.3 yrs. Age, sex, and cumulated comorbidities of the comparison group were not different from the COVID-19 group. A total of 92.6% of COVID-19 patients had a mild or moderate course, two patients had to be referred to acute hospital because of respiratory failure, and one of these patients died in the acute hospital. After implementation of a strict hygiene concept, no further nosocomial COVID-19 infections were detected. The rehabilitation duration was significantly longer in the COVID-19 group (54.2 ± 23.6 days vs. 32.1 ± 17.7 days. Daily therapy duration was 132.3 ± 44 mins before SARS-CoV-2 infection and reduced to 81.9 ± 27.3 mins during COVID-19. After discontinuation of isolation measures, therapy duration increased significantly (99.3 ± 70.2 mins). The baseline Functional Independence Measure score was higher in the COVID-19 group (91.93 ± 25.64 points vs. 82.98 ± 22.73 points) and Functional Independence Measure improvements were lower in COVID-19 patients than in the 2019 comparison group (6.96 ± 8.96 points vs. 20.3 ± 15.98 pointslt; 0.001). COVID-19 infection itself had a strong negative impact on Functional Independence Measure change as identified by regression analysis. Linear regression analysis showed that COVID-19 reduced the Functional Independence Measure at discharge by 8.9 points (95% CI = −14.725 to −3.097, P = 0.003) after correction for Functional Independence Measure at admission, age, sex, and morbidity index at admission. Conclusions COVID-19 had a strong negative impact on rehabilitation benefits as assessed by Functional Independence Measure. Neuromusculoskeletal rehabilitation could be continued, but all patients received less therapy minutes during isolation. After implementation of a strict COVID-19–specific hygiene concept, no further infections were detected.01A - Beitrag in wissenschaftlicher ZeitschriftPublikation RCT abstract - Using a smartphone application in COPD patients to increase physical activity following pulmonary rehabilitation. Results of the AMOPUR Study, a multicenter, randomized, controlled study(European Respiratory Society, 2021) Spielmanns, Marc; Böselt, Tobias; Huber, Stephan; Bollinger, Pawandeep Kaur; Bjoerklund, Jonas; Ulm, Bernhard; Pekacka-Egli, Anna Maria; Leitl, Daniela; Jarosch, Inga; Schneeberger, Tessa; Spielmanns, Sabine; Gloeckl, Rainer; Koczulla, Rembert01A - Beitrag in wissenschaftlicher ZeitschriftPublikation Sonda PEG: przyjaciel czy wróg pacjenta i jego rodziny(Pestka i Ogryzek, 2021) Pekacka-Egli, Anna Maria; Baj-Lieder, Marty; Ulman-Bogusławska, Renata04A - Beitrag SammelbandPublikation Natalia Zylberlast-Zand (1883–1942)(Springer, 2021) Pekacka-Falkowska, Katarzyna; Pekacka-Egli, Anna Maria01A - Beitrag in wissenschaftlicher ZeitschriftPublikation Impact of a smartphone application (KAIA COPD app) in combination with Activity Monitoring as a maintenance prOgram following PUlmonary Rehabilitation in COPD. The protocol for the AMOPUR Study, an international, multicenter, parallel group, randomized, controlled study(BioMed Central, 2020) Spielmanns, Marc; Boeselt, Tobias; Huber, Stephan; Kaur Bollinger, Pawandeep; Ulm, Bernhard; Pekacka-Egli, Anna Maria; Jarosch, Inga; Schneeberger, Tessa; Schoendorf, Sabine; Gloeckl, Rainer; Koczulla, A. RembertAbstract Background Increasing physical activity (PA) is considered to be an important factor for the efficient management of chronic obstructive pulmonary disease (COPD). Successful methods required to achieve improvements in PA following pulmonary rehabilitation (PR), however, are rarely reported. Therefore, we will conduct this trial to evaluate the effectiveness of using a COPD management program delivered to the patient via the KAIA COPD app, a mobile medical application, after the completion of PR. Methods This is the protocol for a randomized, controlled, open-label, multicentered trial that will be carried out at inpatient PR hospital centers in Germany and Switzerland. The interventions will involve the use of the KAIA COPD app program (Arm 1) or an active comparator, i.e., usual care (Arm 2). Patients completing an in-hospital PR program and consenting to participate in the study will be screened with the inclusion and exclusion criteria and enrolled in the study. After fulfilling the screening requirements, the patients will be randomized into one of the two arms with parallel group assignment in a 1:1 ratio. The training program will be delivered to the participants grouped in Arm 1 via the KAIA COPD app and to participants grouped in Arm 2 via the regular recommendations or standard of care by the PI. In total, 104 participants will be included in the trial. The treatment period will last for 24 weeks. Electronic versions of questionnaires will be used to collect patient-reported assessments remotely. The primary outcome measure is the change in physical activity of the intervention group in comparison to the control group, measured over 1 week as the mean steps per day with a Polar A 370 activity tracker, from baseline (end of PR) to the 6-month follow-up. The secondary outcome measures are functional exercise capacity, health status, sleep quality, exacerbation rate, and depression and anxiety symptoms assessed at several intervals. Discussion This study seeks to prove the effects of the KAIA COPD mobile application in COPD patients after PR. The app offers educational, exercise training plus activity monitoring and motivational programs that can be easily implemented in the patient’s home setting, enabling patients to maintain the effects that are typically elicited in the short term after pulmonary rehabilitation for the long term. Trial registration German Clinical Trials Register (DRKS00017275). Protocol version 2.0 dated 3 June 2019.01A - Beitrag in wissenschaftlicher ZeitschriftPublikation Effects of a comprehensive pulmonary rehabilitation in severe post-COVID-19 patients(MDPI, 2021) Spielmanns, Marc; Pekacka-Egli, Anna Maria; Schoendorf, Sabine; Windisch, Wolfram; Hermann, MatthiasBackground: Severe COVID-19 infection often leads to impairments requiring pulmonary rehabilitation (PR) following the acute phase. Little is known about the efficacy of PR in these patients. We therefore compared post-COVID-19 patients (PG) referred to PR patients with other lung diseases (LG). Methods: 99 PG were admitted to PR. In a prospective design, the results of PG were collected and compared to the results of LG of 2019 (n = 419) according to Functional Independence Measurement (FIM), Cumulative Illness Rating Scale (CIRS), 6-min walk test (6-MWT), duration of PR, and Feeling Thermometer (FT). Results: According to age, sex, and CIRS, both groups showed no significant differences. The improvements in the 6-MWT in the pre to post comparison were on average 180 (±101) meters for PG and 102 (±89) meters for LG (p < 0.001). FT showed a significant enhancement for PG of 21 (±14) points and for LG of 17 (±16) points (p < 0.039), while FIM significantly increased by 11 (±10) points in PG and 7 (±8) points in LG (p < 0.001). Conclusions: Comprehensive PR in PG is very effective according to the results in FIM, 6-MWT and FT. Therefore, we recommend PR following severe post-COVID-19 infections.01A - Beitrag in wissenschaftlicher Zeitschrift
