Asprion, Petra

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Asprion, Petra

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Autor:in: Asprion, Petra × Typ: 01A - Beitrag in wissenschaftlicher Zeitschrift ×

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Gerade angezeigt 1 - 9 von 9
  • Vorschaubild
    Publikation
    Peer instruction as teaching method in cybersecurity and data privacy
    (International School for Social and Business Studies, 2023) Schneider, Bettina; Asprion, Petra [in: International Journal of Management, Knowledge and Learning]
    Cybersecurity and data privacy are important fields today. Basic education in these two interconnected areas should already be offered in schools, as practically everyone today can encounter the dangers and risks of the Internet in terms of data theft, data manipulation or the like. However, the topics of cybersecurity and data privacy are generally abstract, and many people are not interested in such rather technical topics. To arouse interest and provide a certain basic education, we used ‘peer instruction’ combined with storytelling as a promising method. Within the framework of an EU project called GEIGER and with the support of students who have learned data privacy by means of the presented method, the method has been further developed, applied, tested, reflected, and iteratively improved. In summary, the method presented is useful for the topics of cybersecurity and data privacy, but the recommendations compiled must be considered in particular with regard to careful preparation and testing.
    01A - Beitrag in wissenschaftlicher Zeitschrift
  • Vorschaubild
    Publikation
    RWD-Cockpit. Application for quality assessment of real-world data
    (JMIR Publications, 18.10.2022) Degen, Markus; Babrak, Lmar; Smakaj, Erand; Agac, Teyfik; Asprion, Petra; Grimberg, Frank; Van der Werf, Daan; Van Ginkel, Erwin Willem; Tosoni, Deniz David; Clay, Ieuan; Brodbeck, Dominique; Natali, Eriberto; Schkommodau, Erik; Miho, Enkelejda [in: JMIR Formative Research]
    Digital technologies are transforming the health care system. A large part of information is generated as real-world data (RWD). Data from electronic health records and digital biomarkers have the potential to reveal associations between the benefits and adverse events of medicines, establish new patient-stratification principles, expose unknown disease correlations, and inform on preventive measures. The impact for health care payers and providers, the biopharmaceutical industry, and governments is massive in terms of health outcomes, quality of care, and cost. However, a framework to assess the preliminary quality of RWD is missing, thus hindering the conduct of population-based observational studies to support regulatory decision-making and real-world evidence.
    01A - Beitrag in wissenschaftlicher Zeitschrift
  • Vorschaubild
    Publikation
    RWD-Cockpit: application for quality assessment of real-world data
    (JMIR Publications, 2022) Babrak, Lmar; Smakaj, Erand; Agac, Teyfik; Asprion, Petra; Grimberg, Frank; Van der Werf, Daan; van Ginkel, Erwin Willem; Tosoni, Deniz David; Clay, Ieuan; Degen, Markus; Brodbeck, Dominique; Natali, Eriberto Noel; Schkommodau, Erik; Miho, Enkelejda [in: JMIR Formative Research]
    Background: Digital technologies are transforming the health care system. A large part of information is generated as real-world data (RWD). Data from electronic health records and digital biomarkers have the potential to reveal associations between the benefits and adverse events of medicines, establish new patient-stratification principles, expose unknown disease correlations, and inform on preventive measures. The impact for health care payers and providers, the biopharmaceutical industry, and governments is massive in terms of health outcomes, quality of care, and cost. However, a framework to assess the preliminary quality of RWD is missing, thus hindering the conduct of population-based observational studies to support regulatory decision-making and real-world evidence. Objective: To address the need to qualify RWD, we aimed to build a web application as a tool to translate characterization of some quality parameters of RWD into a metric and propose a standard framework for evaluating the quality of the RWD. Methods: The RWD-Cockpit systematically scores data sets based on proposed quality metrics and customizable variables chosen by the user. Sleep RWD generated de novo and publicly available data sets were used to validate the usability and applicability of the web application. The RWD quality score is based on the evaluation of 7 variables: manageability specifies access and publication status; complexity defines univariate, multivariate, and longitudinal data; sample size indicates the size of the sample or samples; privacy and liability stipulates privacy rules; accessibility specifies how the data set can be accessed and to what granularity; periodicity specifies how often the data set is updated; and standardization specifies whether the data set adheres to any specific technical or metadata standard. These variables are associated with several descriptors that define specific characteristics of the data set. Results: To address the need to qualify RWD, we built the RWD-Cockpit web application, which proposes a framework and applies a common standard for a preliminary evaluation of RWD quality across data sets—molecular, phenotypical, and social—and proposes a standard that can be further personalized by the community retaining an internal standard. Applied to 2 different case studies—de novo–generated sleep data and publicly available data sets—the RWD-Cockpit could identify and provide researchers with variables that might increase quality Conclusions: The results from the application of the framework of RWD metrics implemented in the RWD-Cockpit application suggests that multiple data sets can be preliminarily evaluated in terms of quality using the proposed metrics. The output scores—quality identifiers—provide a first quality assessment for the use of RWD. Although extensive challenges remain to be addressed to set RWD quality standards, our proposal can serve as an initial blueprint for community efforts in the characterization of RWD quality for regulated settings.
    01A - Beitrag in wissenschaftlicher Zeitschrift
  • Vorschaubild
    Publikation
    CySecEscape 2.0 - A virtual escape room to raise cybersecurity awareness
    (Serious Games Society, 2021) Löffler, Emanuel; Schneider, Bettina; Asprion, Petra; Zanwar, Trupti [in: International Journal of Serious Games]
    An increasing number of small and medium-sized enterprises (SMEs) use the Internet to support and grow businesses. The application of new technologies comes with inherent risks of ever-changing cyberspace and increasing cybercrime. Previous research has shown that the human factor remains the core element in the cybersecurity chain, so it is paramount to make sure the employees receive effective training to embrace a security mindset. This study puts forward previous research that resulted in a portable escape room game to raise cybersecurity awareness. The purpose of the study is to elaborate the transformation of the physical game into a virtual learning experience to increase flexibility in times such as the Covid-19 lockdown. As main method, we applied the design science framework of Hevner et al. As main result, the research elaborates the design of the developed artifact—a virtual prototype of the escape room game addressing the cybersecurity challenges of SMEs. For the evaluation of the prototype, empirical data was collected in a qualitative study. As main conclusions we have observed that a physical escape room setting can be transformed into a virtual setting with little means without sacrificing player immersion. A limitation was identified in teaching targeted social engineering attacks.
    01A - Beitrag in wissenschaftlicher Zeitschrift
  • Vorschaubild
    Publikation
    The real-world data challenges radar: a review on the challenges and risks regarding the use of real-world data
    (Karger, 2021) Grimberg, Frank; Asprion, Petra; Schneider, Bettina; Miho, Enkelejda; Babrak, Lmar; Habbabeh, Ali [in: Digital Biomarkers]
    Background: The life science industry has a strong interest in real-world data (RWD), a term that is currently being used in many ways and with varying definitions depending on the source. In this review article, we provide a summary overview of the challenges and risks regarding the use of RWD and its translation into real-world evidence and provide a classification and visualization of RWD challenges by means of the RWD Challenges Radar. Summary: Based on a systematic literature search, we identified 3 types of challenges – organizational, technological, and people-based – that must be addressed when deriving evidence from RWD to be used in drug approval and other applications. It further demonstrates that numerous different aspects, for example, related to the application field and the associated industry, must be considered. A key finding in our review is that the regulatory landscape must be carefully assessed before utilizing RWD. Key Messages: Establishing awareness and insight into the challenges and risks regarding the use of RWD will be key to taking full advantage of the RWD potential. As a result of this review, an “RWD Challenges Radar” will support the establishment of awareness by providing a comprehensive overview of the relevant aspects to be considered when employing RWD.
    01A - Beitrag in wissenschaftlicher Zeitschrift
  • Vorschaubild
    Publikation
    Data privacy assessment: an exemplary case for higher education institutions
    (International School for Social and Business Studies, 2019) Habbabeh, Ali; Schneider, Bettina; Asprion, Petra [in: International Journal of Management, Knowledge and Learning]
    The European General Data Protection Regulation (GDPR), which has become applicable in May 2018, obliges companies and thus Higher Education Institutions (HEIs) to (re)assess their data privacy procedures in particular the processing of personal data. As the new law unfolds an extraterritorial scope, HEIs located outside the European Union (EU) also need to examine whether they are affected, and, if so, take the necessary measures. There is a lack of discussion and approaches in the current literature as to how HEIs can comply with the GDPR regulations. The aim of this study is therefore to analyse scientific publications in order to deliver two results: Firstly, consolidated relevant recommendations and requirements in the context of GDPR, and, secondly, an instrument to help HEIs to raise their GDPR awareness. The latter was built by applying design science guidelines and resulted on a whole of 44 controls that yield a total score. The resulting value can serve as an indicator of a HEI's accordance with GDPR regulations. In addition, the compiled controls can be used as a management instrument to assess the measures taken and to continuously promote compliance with GDPR.
    01A - Beitrag in wissenschaftlicher Zeitschrift
  • Vorschaubild
    Publikation
    Systems of Engagement. Die digitale Arbeitswelt
    (GITO, 2018) Asprion, Petra; Schneider, Bettina [in: ERP Management]
    Wenn in Unternehmen über die künftige digitale Arbeitswelt nachgedacht wird, stehen auch die monolithischen und wenig flexiblen ERP-Systeme zur Disposition: Inwieweit sind diese tauglich, um die modernen Anforderungen, etwa die Integration von mobilen Endgeräten und interaktiven, intelligenten Apps zu unterstützen? In diesem Beitrag diskutieren wir mit «Systems of Engagement» einen interessanten Ansatz: Die klassi-schen ERP-Systeme werden künftig als «Systems of Record» genutzt, die eine stabile und sichere (Daten-)Plattform für heterogene (mobile) Endgeräte und Applikationen bieten. Diese wiederum stellen sicher, dass künftigen Nutzungsfeldern und anspruchs-vollen Anwendern das Tor zur innovativen digitalen Arbeitswelt weit offensteht.
    01A - Beitrag in wissenschaftlicher Zeitschrift
  • Vorschaubild nicht verfügbar
    Publikation
    Der SoD-Manager im Spannungsfeld zwischen Business und IT
    (Springer, 2009) Asprion, Petra [in: Zeitschrift für Controlling]
    Softwareeinsatz im Compliance-Umfeld bietet Möglichkeiten, kontrollintensive Aufgaben zu automatisieren und gegebenenfalls effizienter und/ oder effektiver zu gestalten. Im Kontext mit der Methode der Funktionstrennung werden interessante Produkte angeboten, die in einigen Unternehmen bereits implementiert sind. Im operativen Betrieb ist eine solche Software jedoch kein Selbstläufer. Um Vorteile aus dem Softwareeinsatz zu generieren, müssen personelle Ressourcen zur Verfügung stehen, die den reibungslosen Ablauf und die Integration der Software koordinieren: Ein „SoD-Manager“, der unterschiedliche Interessen und Anforderungen aus den Fachabteilungen (Business) und den Informatikabteilungen (IT) in Zusammenhang mit der Software handhaben kann. Diese Rolle, die zugehörigen Aufgaben, daraus resultierende Spannungsfelder sowie deren mögliche Bewältigung, stehen im Mittelpunkt dieses Beitrages.
    01A - Beitrag in wissenschaftlicher Zeitschrift
  • Vorschaubild nicht verfügbar
    Publikation
    Compliance und ERP-Systeme: Eine bivalente Beziehung
    (Springer, 2009) Asprion, Petra; Knolmayer, Gerhard [in: Zeitschrift für Controlling & Management]
    ERP-Systeme bieten zahlreiche Kontrollmechanismen an, deren systematische Nutzung unter Wirtschaftlichkeitsgesichtspunkten attraktiv sein kann. ERP General Controls sollen die Ordnungsmäßigkeit des ERP-Einsatzes sicherstellen und sind Voraussetzung, um ein ERP-System als Instrument für Compliance-Nachweise nutzen zu können. ERP Application Controls können als Instrumente genutzt werden, um die Compliance von Geschäftsprozessen nachzuweisen. Die in ERP-Systemen vorgehaltenen Kontrollmechanismen können COBIT-Domänen und -Prozessen zugeordnet werden; wir zeigen dies am Beispiel von SAP ERP.
    01A - Beitrag in wissenschaftlicher Zeitschrift